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BLUE REVIEWSM

for Providers

March 2024

Pharmacy Program Quarterly Update Changes Effective April 1, 2024 – Part 1

Contents
Drug List Changes
Drug List Exclusions/Revisions – Effective April 1, 2024
Balanced Drug List Exclusions
Performance Drug List Exclusions
Performance Select Drug List Exclusions
Health Insurance Marketplace Drug List Exclusions
Basic, Enhanced, Multi-Tier Basic and Multi-Tier Enhanced Revisions
Drug Tier Changes – As of April 1, 2024
Balanced Drug List Tier Changes
Performance Drug List Tier Changes
Performance Select Drug List Tier Changes
Health Insurance Marketplace Exchange Drug List Tier Changes
Utilization Management Program Changes
Additions to Standard Prior Authorization Program – Effective April 1, 2024
Basic, Multi-Tier Basic, Enhanced, Multi-Tier Enhanced Drug Lists, and Health Insurance Marketplace
Balanced, Performance, Performance Select, Basic, Multi-Tier Basic, Enhanced, Multi-Tier Enhanced and Health Insurance Marketplace Drug Lists
Dispensing Limit Changes
Balanced, Performance, Performance Select, Basic, Multi-Tier Basic, Enhanced, Multi-Tier Enhanced and Health Insurance Marketplace Drug Lists
Change in Benefit Coverage for Select High-Cost Products
Pharmacy Benefits Updates
Reminder: BCBSOK Offers LifeScan as Preferred Option for Glucose Management
Reminder: BCBSOK’s Updated Approach to Managing GLP-1 Agonist Medications

Reminder: The Quarterly Pharmacy Changes awareness article is published in two parts. This part 1 article includes changes that require member notification – drug list revisions/exclusions, dispensing limits, utilization management changes and general information on pharmacy benefit program updates. Our intention is to alert you of these changes as our members are receiving letters on changes to their drug list and/or pharmacy benefit. The part 2 article will be published closer to the April 1, 2024, effective date.

Drug List Changes
Based on the availability of new prescription medications and Prime’s National Pharmacy and Therapeutics Committee’s review of changes in the pharmaceuticals market, some revisions (drugs still covered but moved to a higher out-of-pocket payment level) and/or exclusions (drugs no longer covered) will be made to the Blue Cross and Blue Shield of Oklahoma drug lists, effective on or after April 1, 2024.

The April Quarterly Pharmacy Changes Part 2 article with recent coverage additions will be published closer to the April 1 effective date.

Your patient(s) may ask you about therapeutic or lower cost alternatives if their medication is affected by one of these changes.

Drug-list changes are listed on the charts below or you can view current drug lists on our member website.

Drug List Exclusions/Revisions – Effective April 1, 2024

Balanced Drug List Exclusions

Drug1

Alternatives1, 2

Drug Class/Condition

CAROSPIR (spironolactone susp 25 mg/5 ml)

eplerenone tablet, spironolactone tablet, triamterene capsule

Heart Failure, Hypertension, Edema

DIASTAT ACUDIAL (diazepam rectal gel delivery system 10 mg, 20 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Acute Repetitive Seizures

LIVALO (pitavastatin calcium tab 1 mg, 2 mg, 4 mg)

atorvastatin, lovastatin, rosuvastatin, pravastatin, simvastatin

Hyperlipidemia, Hypercholesterolemia

MITIGARE (colchicine cap 0.6 mg)

colchicine tablet 0.6 mg

Gout

NORDITROPIN FLEXPRO (somatropin solution pen-injector 5 mg/1.5 ml, 10 mg/1.5 ml, 15 mg/1.5 ml, 30 mg/3 ml)

GENOTROPIN, OMNITROPE

Growth Hormone Deficiency, Short Stature, Growth Failure

ONEXTON (clindamycin phosphate-benzoyl peroxide gel 1.2%-3.75%)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Acne

OXANDROLONE (oxandrolone tab 2.5 mg, 10 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Promotes Weight Gain

oxandrolone tab 2.5 mg, 10 mg

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Promotes Weight Gain

VOTRIENT (pazopanib hcl tab 200 mg (base equiv))

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

VYVANSE (lisdexamfetamine dimesylate cap 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder

VYVANSE (lisdexamfetamine dimesylate chew tab 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder


Performance Drug List Exclusions

Drug1

Alternatives1, 2

Drug Class/Condition

CROTAN (crotamiton lotion 10%)

permethrin

Scabies

DIASTAT ACUDIAL (diazepam rectal gel delivery system 10 mg, 20 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Acute Repetitive Seizures

FLURAZEPAM HYDROCHLORIDE (flurazepam hcl cap 15 mg, 30 mg)

estazolam, temazepam

Insomnia

INSULIN ASPART (insulin aspart inj soln 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART FLEXPEN (insulin aspart soln pen-injector 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART PENFILL (insulin aspart soln cartridge 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART PROTAMINE/ INSULIN ASPART (insulin aspart prot & aspart (human) inj 100 unit/ml (70-30))

NOVOLOG 70/30

Diabetes

INSULIN ASPART PROTAMINE/ INSULIN ASPART FLEXPEN (insulin aspart prot & aspart sus pen-inj 100 unit/ml (70-30))

NOVOLOG 70/30

Diabetes

NORDITROPIN FLEXPRO (somatropin solution pen-injector 5 mg/1.5 ml, 10 mg/1.5 ml, 15 mg/1.5 ml, 30 mg/3 ml)

GENOTROPIN, OMNITROPE

Growth Hormone Deficiency, Short Stature, Growth Failure

OXANDROLONE (oxandrolone tab 2.5 mg, 10 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Promotes Weight Gain

oxandrolone tab 2.5 mg, 10 mg

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Promotes Weight Gain

SYMJEPI (epinephrine soln prefilled syringe 0.15 mg/0.3 ml (1:2000), 0.3 mg/0.3 ml (1:1000)

epinephrine solution auto-injector, AUVI-Q

Anaphylaxis, Severe Hypersensitivity Reactions

VOTRIENT (pazopanib hcl tab 200 mg (base equiv))

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

VYVANSE (lisdexamfetamine dimesylate cap 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder

VYVANSE (lisdexamfetamine dimesylate chew tab 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder


Performance Select Drug List Exclusions

Drug1

Alternatives1, 2

Drug Class/Condition

CROTAN (crotamiton lotion 10%)

permethrin

Scabies

DIASTAT ACUDIAL (diazepam rectal gel delivery system 10 mg, 20 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Acute Repetitive Seizures

diclofenac potassium (migraine) packet 50 mg

diclofenac tablet

Migraine

FLURAZEPAM HYDROCHLORIDE (flurazepam hcl cap 15 mg, 30 mg)

estazolam, temazepam

Insomnia

LIVALO (pitavastatin calcium tab 1 mg, 2 mg, 4 mg)

atorvastatin, lovastatin, rosuvastatin, pravastatin, simvastatin

Hyperlipidemia, Hypercholesterolemia

NORDITROPIN FLEXPRO (somatropin solution pen-injector 5 mg/1.5 ml, 10 mg/1.5 ml, 15 mg/1.5 ml, 30 mg/3 ml)

GENOTROPIN, OMNITROPE

Growth Hormone Deficiency, Short Stature, Growth Failure

ONEXTON (clindamycin phosphate-benzoyl peroxide gel 1.2%-3.75%)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Acne

OXANDROLONE (oxandrolone tab 2.5 mg, 10 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Promotes Weight Gain

oxandrolone tab 2.5 mg, 10 mg

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Promotes Weight Gain

VOTRIENT (pazopanib hcl tab 200 mg (base equiv))

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

VYVANSE (lisdexamfetamine dimesylate cap 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder

VYVANSE (lisdexamfetamine dimesylate chew tab 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder


Health Insurance Marketplace (HIM) Drug List Exclusions

Drug1

Alternatives1, 2

Drug Class/Condition

FLURAZEPM HYDROCHLORIDE (flurazepam hcl cap 15 mg, 30 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Insomnia

INSULIN ASPART (insulin aspart inj soln 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART FLEXPEN (insulin aspart soln pen-injector 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART PENFILL (insulin aspart soln cartridge 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART PROTAMINE/INSULIN ASPART (insulin aspart prot & aspart (human) inj 100 unit/ml (70-30))

NOVOLOG 70/30

Diabetes

NORDITROPIN FLEXPRO (somatropin solution pen-injector 5 mg/1.5 ml, 10 mg/1.5 ml, 15 mg/1.5 ml, 30 mg/3 ml)

GENOTROPIN, OMNITROPE
Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Growth Hormone Deficiency, Short Stature, Growth Failure

OXANDROLONE (oxandrolone tab 2. mg, 10 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Weight Gain

SYMJEPI (epinephrine soln prefilled syringe 0.15 mg/0.3 ml (1:2000), 0.3 mg/0.3 ml (1:1000)

epinephrine (generic Epi-Pen), AUVI-Q

Anaphylaxis, Severe Hypersensitivity Reactions

VOTRIENT (pazopanib hcl tab 200 mg (base equiv))

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

VYVANSE (lisdexamfetamine dimesylate cap 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder

VYVANSE (lisdexamfetamine dimesylate chew tab 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder


Basic, Enhanced, Multi-Tier Basic and Multi-Tier Enhanced Revisions

Drug1

Preferred Alternatives1, 2

Drug Class/Condition

DIASTAT ACUDIAL (diazepam rectal gel delivery system 10 mg, 20 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Acute Repetitive Seizures

INSULIN ASPART (insulin aspart inj soln 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART FLEXPEN (insulin aspart soln pen-injector 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART PENFILL (insulin aspart soln cartridge 100 unit/ml)

NOVOLOG

Diabetes

INSULIN ASPART PROTAMINE/INSULIN ASPART (insulin aspart prot & aspart (human) inj 100 unit/ml (70-30))

NOVOLOG 70/30

Diabetes

INSULIN ASPART PROTAMINE/INSULIN ASPART FLEXPEN (insulin aspart prot & aspart sus pen-inj 100 unit/ml (70-30))

NOVOLOG 70/30

Diabetes

NORDITROPIN FLEXPRO (somatropin solution pen-injector 5 mg/1.5 ml, 10 mg/1.5 ml, 15 mg/1.5 ml, 30 mg/3 ml)

GENOTROPIN, OMNITROPE

Growth Hormone Deficiency, Short Stature, Growth Failure

SYMJEPI (epinephrine soln prefilled syringe 0.15 mg/0.3 ml (1:2000), 0.3 mg/0.3 ml (1:1000)

epinephrine (generic Epi-Pen),
AUVI-Q

Anaphylaxis, Severe Hypersensitivity Reactions

VOTRIENT (pazopanib hcl tab 200 mg (base equiv))

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

VYVANSE (lisdexamfetamine dimesylate cap 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, 70 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder

VYVANSE (lisdexamfetamine dimesylate chew tab 10 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg)

There is a generic equivalent available. Please talk to your doctor or pharmacist about other medication(s) available for your condition.

ADHD, Binge Eating Disorder


Drug Tier Changes – As of April 1, 2024
The tier changes listed below apply to members on a managed drug list. Members may pay more for these drugs after April 1, 2024.

Balanced Drug List Tier Changes

Drug1

Alternatives1, 2

Drug Class/Condition

New Tier

AMCINONIDE (amcinonide oint 0.1%)

fluocinonide cream 0.5%, betamethasone dipropionate augmented cream 0.05%, betamethasone dipropionate oint 0.05%

Inflammatory Conditions

Non-Preferred Brand

HYDROCODONE POLISTIREX/CH LORPHENIRAMINE POLISTIREX (hydrocod polst-chlorphen polst er susp 10-8 mg/5 ml)

benzonatate, hydrocodone bitartrate/homatropine methylbromide, promethazine hydrochloride/dextromethorphan hydrobromide, promethazine/codeine, promethazine/dextromethorphan

Upper Respiratory Symptoms

Non-Preferred Brand

MELPHALAN (melphalan tab 2 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

Non-Preferred Brand

MIGLITOL (miglitol tab 25 mg, 50 mg, 100 mg)

acarbose

Diabetes

Non-Preferred Brand


Performance Drug List Tier Changes
Drug1 Alternatives1, 2 Drug Class/Condition New Tier

HYDROCODONE POLISTIREX/CHLORPHENIRAMINE POLISTIREX (hydrocod polst-chlorphen polst er susp 10-8 mg/5 ml)

benzonatate, hydrocodone bitartrate/homatropine methylbromide, promethazine hydrochloride/dextromethorphan hydrobromide, promethazine/codeine, promethazine/dextromethorphan

Upper Respiratory Symptoms

Non-Preferred Brand

MELPHALAN (melphalan tab 2 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

Non-Preferred Brand

MIGLITOL (miglitol tab 25 mg, 50 mg, 100 mg)

acarbose

Diabetes

Non-Preferred Brand


Performance Select Drug List Tier Changes

Drug1

Alternatives1, 2

Drug Class/Condition

New Tier

HYDROCODONE POLISTIREX/CHLORPHENIRAMINE POLISTIREX (hydrocod polst-chlorphen polst er susp 10-8 mg/5 ml)

benzonatate, hydrocodone bitartrate/homatropine methylbromide, promethazine hydrochloride/dextromethorphan hydrobromide, promethazine/codeine, promethazine/dextromethorphan

Upper Respiratory Symptoms

Non-Preferred Brand

MELPHALAN (melphalan tab 2 mg)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Cancer

Non-Preferred Brand

MIGLITOL (miglitol tab 25 mg, 50 mg, 100 mg)

acarbose

Diabetes

Non-Preferred Brand


Health Insurance Marketplace Exchange (HIE) Drug List Tier Changes

Drug1

Alternatives1, 2

Drug Class/Condition

New Tier

HYDROCODONE POLISTIREX/CHLORPHENIRAMINE POLISTIREX (hydrocod polst-chlorphen polst er susp 10-8 mg/5 ml)

Please talk to your doctor or pharmacist about other medication(s) available for your condition.

Upper Respiratory Symptoms

Non-Preferred Brand


Utilization Management Program Changes

Utilization Management programs are implemented to regularly review the appropriateness of medications within drug-therapy programs, and as a result, may adjust dispensing limits, prior authorization or step-therapy requirements. The following drug programs reflect those changes.

Additions to Standard Prior Authorization Program – Effective April 1, 2024
Several drug categories and/or targeted medications will be added to the Prior Authorization programs for standard pharmacy benefit plans. This includes ASO groups with a standard UM package and/or subcategory selection with auto updates. For groups that have not selected the auto update, these programs will be available to be added to their benefit design as of the program effective date.
Members were notified about the Prior Authorization Standard Program Changes listed in the table below.

Basic, Multi-Tier Basic, Enhanced, Multi-Tier Enhanced Drug Lists, and Health Insurance Marketplace (HIM)

Drug Category

Targeted Medication(s)1 Added

Rapid to Intermediate Acting Insulin PAQL

Insulin Aspart, Insulin Aspart Mix, Insulin Lispro


Balanced, Performance, Performance Select, Basic, Multi-Tier Basic, Enhanced, Multi-Tier Enhanced and Health Insurance Marketplace (HIM) Drug Lists

Drug Category

Targeted Medication(s)1 Added

Therapeutic Alternatives PAQL

Cambia/diclofenac 50 mg packet, Flurazepam* 15 mg, 30 mg capsules


Dispensing Limit Changes
BCBSOK’s prescription-drug benefit program includes coverage limits on certain medications and drug categories. Dispensing limits are based on U.S. Food and Drug Administration approved dosage regimens and product labeling.

BCBSOK may send letters to all members with a claim for a drug included in the Dispensing Limit Program, regardless of the prescribed dosage. This means members may receive a letter even though their prescribed dosage doesn’t meet or exceed the dispensing limit.

For the most up-to-date drug list and list of drug dispensing limits, visit the provider pharmacy webpage.

If your patients have any questions about their pharmacy benefits, please advise them to contact the number on their member ID card. Members may also visit bcbsok.com and log in to Blue Access for MembersSM or MyPrime.com for more online resources.

Dispensing Limit changes are on the chart below with their effective date. Visit bcbsok.com for the most up-to-date drug lists and dispensing limits.

Balanced, Performance, Performance Select, Basic, Multi-Tier Basic, Enhanced, Multi-Tier Enhanced and Health Insurance Marketplace (HIM) Drug Lists

Effective Date

Program

Target Agent

Dispensing Limit

4/1/2024

Xdemvy QL

Xdemvy (lotilaner ophth) soln 0.25%

1 bottle per 50 days


Members were not lettered on these changes.

Change in Benefit Coverage for Select High-Cost Products
Several high-cost products with available lower cost alternatives will be excluded on the pharmacy benefit for select drug lists. This change impacts BCBSOK members who have prescription-drug benefits administered by Prime Therapeutics†. This change is part of an ongoing effort to make sure our members and employer groups have access to safe, cost-effective medications.

Please note: Members were not notified of this change because either there is no utilization, or the pharmacist can easily fill a member's prescription with the equivalent without needing a new prescription from the doctor. The following drugs are excluded on select drug lists.

Product(s) No Longer Covered1

Condition

Covered Alternative(s)1, 2

DICLOFENAC POTASSIUM 25 MG TABLETS

Pain

DICLOFENAC POTASSIUM 50 MG, MELOXICAM, IBUPROFEN, NAPROXEN


Pharmacy Benefits Updates
Reminder: BCBSOK Offers LifeScan as Preferred Option for Glucose Management
New for Members with Diabetes: LifeScan® One Touch test strips and supplies are now preferred options for BCBSOK members with diabetes (effective Jan. 1, 2024). LifeScan products include the OneTouch family of meters, such as the OneTouch Verio Reflect®, Verio Flex®, Ultra Plus Flex™, and Ultra 2® test strips and supplies.

All preferred diabetic glucose-monitoring devices and supplies are available to members with Prime Therapeutics as their pharmacy benefit manager.

Free Glucose Monitor: Members may use a coupon in our member flier for a free, blood-glucose monitor from either preferred vendor.

Reminder: BCBSOK’s Updated Approach to Managing GLP-1 Agonist Medications
BCBSOK is committed to providing its members access to safe, appropriate, and cost-effective health care within their plan benefits. To ensure the appropriate use of GLP-1s as indicated for diabetes, we are making it easier for providers to bypass our prior authorization process for some of our members with diabetes.
Note: Members may have received a letter regarding this change. For more information, review the full article.

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The above material is for informational purposes only and is not a substitute for the independent medical judgment of a physician or other health care provider. Physicians and other health care providers are encouraged to use their own medical judgment based upon all available information and the condition of the patient in determining the appropriate course of treatment. The fact that a service or treatment is described in this material is not a guarantee that the service or treatment is a covered benefit and members should refer to their certificate of coverage for more details, including benefits, limitations and exclusions. Regardless of benefits, the final decision about any service or treatment is between the member and their health care provider.

Prime Therapeutics LLC is a pharmacy benefit management company. BCBSOK contracts with Prime to provide pharmacy benefit management and related other services. BCBSOK, as well as several independent Blue Cross and Blue Shield Plans, has an ownership interest in Prime. MyPrime.com is an online resource offered by Prime Therapeutics.